ET-1 plasma levels, choroidal thickness and multifocal electroretinogram in retinitis pigmentosa

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ET-1 Plasma Levels, Aqueous Flare, and Choroidal Thickness in Patients with Retinitis Pigmentosa

Purpose. To assess endothelin-1 (ET-1) plasma levels, choroidal thickness, and aqueous flare in patients with early stage retinitis pigmentosa (RP) and to search for possible correlations. Methods. We compared 24 RP patients with 24 healthy controls. Choroidal thickness and aqueous flare were measured, respectively, by using a spectral domain optical coherence tomography and a laser flare-cell ...

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Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity in retinitis pigmentosa

INTRODUCTION Our purpose was to study the correlation between the macular morphology and function in eyes with retinitis pigmentosa (RP). METHODS Sixty-six eyes from 33 patients with RP and with different visual acuity (VA) were studied using optical coherence tomography (OCT) and multifocal electroretinogram (mfERG). Correlation analysis was performed between VA, macular thickness, mfERG amp...

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Light adaptation of the electroretinogram. Diminished in retinitis pigmentosa.

The cone electroretinogram has been examined at different levels of ganzfeld adaptation in normals and subjects with retinitis pigmentosa (RP). As light adaptation increases, the amplitude and time course (measured as b-wave implicit time) of the cone ERG decrease in both normal and RP subjects. The same level of light adaptation, however, decreases the amplitude and the implicit time more in n...

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Low levels of plasma endothelin-1 in patients with retinitis pigmentosa

PURPOSE The aim of this study was to elucidate the role of endothelin-1 (ET-1) in the pathophysiology of retinitis pigmentosa (RP). METHODS Plasma ET-1 levels and ophthalmic features in 50 RP patients were compared with those in 20 healthy-eye control subjects. Plasma ET-1 concentrations were determined using a commercially available enzyme-linked immunosorbent assay kit. RESULTS Mean plasm...

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Multifocal electroretinogram in myopia.

PURPOSE To investigate early changes of retinal function in myopic eyes, patients with various degrees of myopia underwent multifocal electroretinography (multifocal ERG). METHODS Thirty young patients (mean age, 26.1 years) were divided into three groups according to the degree of refractive error: emmetropia/low, medium, and high myopia. All groups were matched by sex and age. All subjects ...

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ژورنال

عنوان ژورنال: Life Sciences

سال: 2013

ISSN: 0024-3205

DOI: 10.1016/j.lfs.2013.12.084